Steroid asthma pregnancy

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Dr. Rymer is currently researching regulation of movement in normal and neurologically disordered human subjects, including sources of altered motoneuronal behavior in hemispheric stroke survivors, using electro-physiological, pharmacological, and biomechanical techniques. He currently serves as Director of the Single Motor Unit Laboratory of the Shirley Ryan AbilityLab (SRALab, formerly known as the Rehabilitation Institute of Chicago, or RIC). From 1987-2017 he served as Director of the Sensory Motor Performance Program at RIC, and was RIC’s Vice President for Research from 2008-2014. He is the most senior scientist at SRALab and the founder of many of its current research programs. Dr. Rymer has established himself as one of the most successful mentors of junior faculty, and has been able to relate to the many backgrounds that can contribute to rehabilitation research. In addition to his roles at SRALab, he holds appointments as Professor of PM&R, Physiology, and Biomedical Engineering at the Northwestern University Feinberg School of Medicine.

During conventional pharmacologic dose corticosteroid therapy, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation. Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone (10 mg) as opposed to a quarter of that dose administered every six hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used. Further, it has been shown that a single dose of certain corticosteroids will produce adrenal cortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenal cortical suppression for 1¼ to 1½ days following a single dose) and thus are recommended for alternate day therapy.

VIRAL PNEUMONIA. Clinical symptoms due to influenza A infection include high fever, coryza, headache, malaise, muscle aches, and cough, which usually subside in approximately 3 to 5 days. If chest symptoms persist for longer, a complicating pneumonia should be suspected. Pneumonia can occur from a viral inflammation of lung parenchyma or from a secondary bacterial infection. Amantadine (FDA category C) may be used to treat severe viral pneumonia and can also be used as prophylaxis in high-risk patients. Rimantadine, a newer antiviral agent, has not been studied in pregnant women; however, it has been reported to produce fetal abnormalities when given to animals in doses higher than the recommended dose for humans. 48 It is also currently listed as FDA category C. Ribavirin is effective against both influenza A and B but is listed as FDA category X. Although influenza vaccination is not recommended for all pregnant women, it may be used in high-risk patients and should be given after the first trimester. 46 , 49

Steroid asthma pregnancy

steroid asthma pregnancy

VIRAL PNEUMONIA. Clinical symptoms due to influenza A infection include high fever, coryza, headache, malaise, muscle aches, and cough, which usually subside in approximately 3 to 5 days. If chest symptoms persist for longer, a complicating pneumonia should be suspected. Pneumonia can occur from a viral inflammation of lung parenchyma or from a secondary bacterial infection. Amantadine (FDA category C) may be used to treat severe viral pneumonia and can also be used as prophylaxis in high-risk patients. Rimantadine, a newer antiviral agent, has not been studied in pregnant women; however, it has been reported to produce fetal abnormalities when given to animals in doses higher than the recommended dose for humans. 48 It is also currently listed as FDA category C. Ribavirin is effective against both influenza A and B but is listed as FDA category X. Although influenza vaccination is not recommended for all pregnant women, it may be used in high-risk patients and should be given after the first trimester. 46 , 49

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