17beta hydroxysteroid dehydrogenase 3 deficiency

17β-Hydroxysteroid dehydrogenases ( 17β-HSD , HSD17B ) ( EC ), also 17-ketosteroid reductases ( 17-KSR ), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism . [1] [2] [3] [4] [5] This includes interconversion of DHEA and androstenediol , androstenedione and testosterone , and estrone and estradiol . [6] [7]

Arlan L Rosenbloom, MD  Adjunct Distinguished Service Professor Emeritus of Pediatrics, University of Florida College of Medicine; Fellow of the American Academy of Pediatrics; Fellow of the American College of Epidemiology

Arlan L Rosenbloom, MD is a member of the following medical societies: American Academy of Pediatrics , American College of Epidemiology , American Pediatric Society , Endocrine Society , Pediatric Endocrine Society , Society for Pediatric Research , Florida Chapter of The American Academy of Pediatrics, Florida Pediatric Society , International Society for Pediatric and Adolescent Diabetes

Disclosure: Nothing to disclose.

This gene encodes a member of the aldo/keto reductase superfamily , which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [7]

PricePlow may be willing to pay for blood tests for a trusted reviewer/logger if you can get the product, so long as we can publish the tests. See our blog post about PricePlow’s Blood Testing Program . Who Should Use This? Age and Gender Recommendations At PricePlow we recommend only users above the age of 23 use anabolic compounds due to the fact that estrogenic compounds can close growth plates in the hips and spine, [34,35,36,37] resulting in the user not being able to grow any taller than they naturally would. 19-nor-DHEA falls into the category of being estrogenic and progesteronic, unfortunately, so this would be another compound to avoid for younger lifters.

17beta hydroxysteroid dehydrogenase 3 deficiency

17beta hydroxysteroid dehydrogenase 3 deficiency

PricePlow may be willing to pay for blood tests for a trusted reviewer/logger if you can get the product, so long as we can publish the tests. See our blog post about PricePlow’s Blood Testing Program . Who Should Use This? Age and Gender Recommendations At PricePlow we recommend only users above the age of 23 use anabolic compounds due to the fact that estrogenic compounds can close growth plates in the hips and spine, [34,35,36,37] resulting in the user not being able to grow any taller than they naturally would. 19-nor-DHEA falls into the category of being estrogenic and progesteronic, unfortunately, so this would be another compound to avoid for younger lifters.

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